Postive Psychosocial Exposome
Exploring the science of human flourishing
Founding scientific community
The Positive Psychosocial Exposome Initiative is being developed through an international community spanning exposome science, ageing biology, immunology, neuroscience, preventive medicine, multi-omics, AI and real-world translation.
The Human Exposome Project provides the Initiative's overarching scientific context. Founding Scientific Advisers include Prof David Furman and Prof Eric Verdin (Buck Institute for Research on Aging), Prof Denis Sarigiannis, Prof Fenna Sille (Johns Hopkins Bloomberg School of Public Health), Dr Richard Siow (Ageing Research at King's), Prof Evelyne Bischof, Dr Carina Kern and Founding academic relationships are being developed with Johns Hopkins University around research governance, study design and publication strategy, and King's College London around ageing, brain health and translational research.
A growing technology ecosystem provides complementary measurement and data capabilities, including OpenCures, EXPIN, Humanity, Muse, AWEAR and GlycanAge. Together, partners contribute to a shared, platform-agnostic scientific architecture rather than a supplier ecosystem.
The Positive Psychosocial Exposome Initiative is an international scientific and translational platform dedicated to advancing understanding of how beneficial positive psychosocial exposures influence human biology and contribute to resilience, wellbeing and healthy longevity.
Building upon the foundations established by the Human Exposome Project, the Initiative extends exposome science into an emerging domain that has received comparatively little systematic investigation: the biological consequences of positive psychosocial experiences.
Rather than viewing music, movement, creativity, friendship, belonging and purpose simply as lifestyle choices or psychological constructs, the Initiative conceptualises them as beneficial positive psychosocial exposures that interact continuously with biological systems throughout the life course.
Through international collaboration spanning exposomics, systems biology, neuroscience, neurotechnology, artificial intelligence and translational medicine, the Initiative aims to establish the scientific foundations of the Positive Psychosocial Exposome.
The Initiative is organised around three interconnected objectives:
Scientific Discovery
To understand how beneficial positive psychosocial exposures become biologically embedded through interactions with molecular, physiological, neurological and behavioural systems.
Measurement Innovation
To develop and validate integrated biological and digital biomarkers — including next-generation EEG-derived biomarkers — that objectively characterise positive psychosocial exposures and their effects.
Translation
To convert scientific discovery into evidence-informed Healthy Interventions delivered through products, services, experiences and environments that promote human flourishing across the lifespan.
The Initiative’s flagship research programme, The JoyScore Experiment, provides the first integrated research platform for achieving these objectives through real-world longitudinal studies combining deep multi-omic phenotyping, neuroscience, wearable technologies and artificial intelligence.
Beyond the flagship programme, the Initiative establishes an international collaborative ecosystem connecting researchers, clinicians, technology innovators, governments, developers, cultural organisations and communities to accelerate discovery, methodology confirmation and implementation.
Its ultimate ambition is to create a future in which scientifically validated Healthy Interventions become an integral component of preventive health, clinical practice, healthy buildings, healthy communities and healthy cities.
JoyScore: from the dance floor to everyday life
The JoyScore Experiment began by asking a simple question: can we measure what happens when people experience joy and connection together?
Using the dance floor as a real-world laboratory, early studies explored how music, movement, synchrony and social connection influence the brain, body and biomarkers of health.
Visit Longevity Rave website here to find out more how music, dance and synchrony can create healthy interventions for clubs, spas, hotels and community spaces.